CASE REPORT

The management of nodulocystic acne and hidradenitis suppurativa associated with intestinal dysbiosis

This is a case report performed with ETHEREA-MX® and LongPulse® and ProDeep® handpieces.

Dr. Jose David Alfonzo

Aesthetic Medicine

Treatment

Nodulocystic acne and hidradenitis suppurativa are chronic inflammatory skin diseases with a significant impact on patients' quality of life. Nodulocystic acne is characterized by the presence of deep nodules and cysts that often leave permanent scars, while hidradenitis suppurativa manifests as painful abscesses, fistulous tracts, and recurrent lesions.


Both pathologies share common pathophysiological mechanisms, including innate immune dysfunction, excessive production of pro-inflammatory cytokines, and alterations in the skin and gut microbiota.


Treatment may involve topical and systemic medications, such as antibiotics, retinoids, and immunomodulators, as well as surgical approaches in advanced cases. The use of laser technologies has gained prominence as an adjuvant alternative. The micropulsed 1,064 nm Nd:YAG laser promotes selective destruction of sebaceous glands, has an anti-inflammatory effect, and reduces the formation of new lesions. Due to its greater absorption by water, 1,340 nm Nd:YAP generates controlled tissue heating, enhancing anti-inflammatory action and helping to improve chronic inflammation present in both nodulocystic acne and hidradenitis suppurativa.


The LongPulse® (1,064 nm) and ProDeep® Nd:YAP (1,340 nm) handpieces are compatible with the ETHEREA-MX® and ZYE® platforms. In the clinical case presented, a comprehensive therapeutic approach was implemented that included pharmacological treatment along with the use of several technologies: photodynamic therapy with light and LED, and the LongPulse® and ProDeep® lasers.

Result
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